Replacement therapy of hypothyroidism: Whether the use of levothyroxine is adequate?
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1000-6699.2015.04.003
   		
        
        	
        		- VernacularTitle:甲状腺功能减退症替代治疗:使用左旋甲状腺素是否充足?
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Hui ZHU
			        		
			        		;
		        		
		        		
		        		
			        		Chao LIU
			        		
			        		;
		        		
		        		
		        		
			        		Keying CAI
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Hypothyroidism;
			        		
			        		
			        		
				        		Levothyroxine;
			        		
			        		
			        		
				        		Combination therapy
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Endocrinology and Metabolism
	            		
	            		 2015;31(4):296-299
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Hypothyroidism is a common endocrine disease.Its treatment depends on thyroid hormone replacement therapy.Currently,levothyroxine (L-T4) is the preparation recommended by many guidelines.However,there are some L-T4-treated patients with normal TSH levels and persistent non-specific symptoms and discomforts.Therefore,combination therapy with L-T4and liothyronine (L-T3) has been considered as an alternative option for hypothyroidism.However,more prospective studies are needed to provide evidence-based effects for this kind of regimen.