A diagnostic meta-analysis：fiberoptic ductoscope versus galactography for the diagnostic value of nipple discharge

VernacularTitle:乳管镜与乳管造影对乳头溢液疾病诊断价值比较的meta分析
Author: Minggang FU ; Sha LIU ; Liying GUO
Publication Type:Journal Article
Keywords: Endoscopes; Galactography; Nipple discharge; Meta-analysis
From: The Journal of Practical Medicine 2015;(12):2010-2013
CountryChina
Language:Chinese
Abstract: Objective To evaluate the diagnostic efficiency of fiberoptic ductoscope versus galactography for nipple discharge. Methods Literatures on comparing the diagnostic value of galactography with fiberoptic ductoseope (FDS) on the nipple discharge were searched from the Cochrane library, Evidence based medicine (EBM ),PubMed,China Vip database, and 8 studies were intaked. Then the data was analyzed by software Metadisc1.4 and Review Manager5.1. Results There are 1170 patients in the 8 studies. The pooled estimates for sensitivity of FDS and galactography was 82%, 78%, and the pooled estimates for specificity was 51%, 50%, respectively. The weighted AUC (area under curve) was 0.776, 0.705, Q*values was 0.715, 0.657, respectively. The sensitivities and specificity of the 2 methods were not significantly different. The overall diagnostic efficacy of FDS was better than that of galactography. Conclusion FDS is better than galaetography in the diagnostic value of nipple discharge.