Optimization of low-dose protocol in thoracic aorta CTA : weighting of adaptive statistical iterative reconstruction (ASIR) algorithm and scanning parameters
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.0254-5098.2014.11.019
   		
        
        	
        		- VernacularTitle:胸主动脉CT血管造影自适应性统计迭代重建权重和低剂量扫描条件的优化
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yongxia ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Jin CHANG
			        		
			        		;
		        		
		        		
		        		
			        		Ziwei ZUO
			        		
			        		;
		        		
		        		
		        		
			        		Changda ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Tianle ZHANG
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Adaptive statistical iterative reconstruction;
			        		
			        		
			        		
				        		Radiation dose;
			        		
			        		
			        		
				        		Image quality;
			        		
			        		
			        		
				        		Thoracic aorta CTA
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Radiological Medicine and Protection
	            		
	            		 2014;34(11):867-869
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate the best weighting of adaptive statistical iterative reconstruction (ASIR) algorithm and optimized low-dose scanning parameters in thoracic aorta CT angiography(CTA).Methods Totally 120 patients with the body mass index (BMI) of 19-24 were randomly divided into 6 groups.All patients underwent thoracic aorta CTA with a GE Discovery CT 750 HD scanner (ranging from 290-330 mm).The default parameters (100 kV,240 mAs) were applied in Group 1.Reconstructions were performed with different weightings of ASIR (10%-100% with 10%),and the signal to noise ratio (S/N) and contrast to noise ratio (C/N) of images were calculated.The images of series were evaluated by 2 independent radiologists with 5-point-scale and lastly the best weighting were revealed.Then the mAs in Group 2-6 were defined as 210,180,150,120 and 90 with the kilovoltage 100.The CTDIvoland DLP in every scan series were recorded and the effective dose (E) was calculated.The S/N and C/N were calculated and the image quality was assessed by two radiologists.Results The best weighing of ASIR was 60% at the 100 kV,240 mAs.Under 60% of ASIR and 100 kV,the scores of image quality from 240 mAs to 90 mAs were(4.78 ±0.30)-(3.15 ±0.23).The CTDIvol and DLP were 12.64-4.41 mGy and 331.81-128.27 mGy,and the E was 4.98-1.92 mSv.The image qualities among Group 1-5 were nor significantly different (F =5.365,P > 0.05),but the CTDIvol and DLP of Group 5 were reduced by 37.0% and 36.9%,respectively compared with Group 1.Conclusions In thoracic aorta CT Angiography,the best weighting of ASIR is 60%,and 120 mAs is the best mAs with 100 kV in patients with BMI 19-24.