Study on the quality standard of common selfheal fruit-spike granules
10.3760/cma.j.issn.1673-4246.2015.05.012
- VernacularTitle:夏枯草配方颗粒质量标准研究
- Author:
Wei GONG
;
Xu SUN
;
Kun ZHANG
;
Zhongliang LIU
;
Qinghua ZHAO
;
Xingdong LI
;
Mei ZHAO
;
Xinxin ZHANG
- Publication Type:Journal Article
- Keywords:
Common selfheal fruit-spike granules;
Quality standard;
Rosmarinicacid
- From:
International Journal of Traditional Chinese Medicine
2015;(5):435-438
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish the quality standard of common selfheal fruit-spike granules. Mehtods Rosmarinicacid in the granules were identified by TLC. The extractives were tested by the method for determination of water-soluble extractives. The contents of rosmarinicacid were determined by HPLC. Results TLC had obvious characteristics with the spots clear and well-separated. The extraction limit was no less than 10.0%. Rosmarinicacid showed a good linear relationship at 0.062 5~2.008 0 mg/ml (r=0.999 8,n=6) with average recovery of 99.50% (RSD=1.21%,n=9). The content limitation of rosmarinicacid was discussed as 10.0 mg per pack according to the experiment data.Conclusion The method is easy-operated and accurate which has a good specificity for the quality control of common selfheal fruit-spike granules.
