Microfracture and osteochondral transplantation in the treatment of articular cartilage defects
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.2095-4344.2015.15.004
   		
        
        	
        		- VernacularTitle:软骨移植与软骨微骨折方法修复关节软骨损伤
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jian YANG
			        		
			        		;
		        		
		        		
		        		
			        		Xianlun PANG
			        		
			        		;
		        		
		        		
		        		
			        		Jiangmeng HE
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Subject headings:Fractures,Bone;
			        		
			        		
			        		
				        		Cartilage;
			        		
			        		
			        		
				        		Bone Transplantation
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Tissue Engineering Research
	            		
	            		 2015;(15):2315-2319
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND:Both microfracture and osteochondral transplantation are effective tools in the clinical treatment of articular cartilage defects. 
 OBJECTIVE: To observe the implementation results of microfracture and osteochondral transplantation in the treatment of articular cartilage defects. 
 METHODS:The clinical data of 50 cases (50 knees) of articular cartilage defects were retrospectively analyzed. There were two groups according to surgical repair methods: autogenous osteochondral transplantation+ microfracture in observation group (n=25), and microfracture in control group (n=25). Patients in the two groups were folowed up for over 24 hours to compare the Hospital for Special Surgery scores, clinical efficacy, adverse effects and complications. 
 RESULTS AND CONCLUSION:The number of patients whose Hospital for Special Surgery score was > 85 points and 60 to 85 points in the observation group was significantly larger than that in the control group (P< 0.05), and the total treatment effective rate of patients in the observation group was significantly higher than that of the control group (92%vs. 60%,P < 0.05). No complications occurred in both two groups. These findings indicate that osteochondral transplantation has better implementation results in the treatment of articular cartilage defects than microfracture.