Cytokeratin 14 and cancer
10.3760/cma.j.issn.1673-422X.2015.06.009
- VernacularTitle:细胞角蛋白14与肿瘤
- Author:
Weiquan ZHANG
;
Xiaogang ZHAO
- Publication Type:Journal Article
- Keywords:
Keratin-1 4;
Tumor markers,biological;
Neoplasms
- From:
Journal of International Oncology
2015;(6):436-438
- CountryChina
- Language:Chinese
-
Abstract:
Cytokeratin 1 4 (CK1 4)has a different degree of expression in NSCLC,breast cancer,cer-vical cancer,esophageal cancer and other tumors,except in the normal basal cells.CK1 4 is mainly expressed in the peripheral part of the tumor,which is rarely expressed in the non-aggressive part.Usually the higher malignant of the tumor has the more expression of CK1 4.Given all that,CK1 4 gene plays an important role in the tumor progression and metastasis in a variety of tumors,which can be considered as an biomarker being used in the diagnosis,treatment and prognosis evaluation.
