Research Progress in Anti-tumor Mechanisms of Platycodin-D
10.3969/j.issn.1005-5304.2015.02.040
- VernacularTitle:桔梗皂苷-D抗肿瘤机制研究进展
- Author:
Ruolin ZHAO
;
Xu ZHANG
;
Meijuan CHEN
;
Kunfu ZHOU
- Publication Type:Journal Article
- Keywords:
platycodin-D;
tumor;
mechanism;
apoptosis;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(2):126-129
- CountryChina
- Language:Chinese
-
Abstract:
Platycodin-D (PD) is the major monomer of triterpene saponins in the root of Platycodon grandiflorum. Recent studies have demonstrated that PD has a wide range of anti-tumor effect and its efficacy is satisfying. This article reviewed anti-tumor mechanisms of PD from the aspects of proliferation, apoptosis, invasion and metastasis, immune and anti-inflammation, etc., with a purpose to provide a theoretical basis and reference for the further development and better utilization of PD and taking its anti-tumor advantage.
