Fabrication of New GH-CS/Fc-NH2/Cytc Modified Electrode and Its Application in Detection of Nitrite
10.11895/j.issn.0253-3820.140737
- VernacularTitle:新型石墨烯-壳聚糖/二茂铁衍生物/细胞色素c修饰电极的制备及其用于亚硝酸钠的检测研究
- Author:
Na HUANG
;
Meiling LIU
;
Jianhui DENG
;
Linping WANG
;
Youyu ZHANG
;
Shouzhuo YAO
- Publication Type:Journal Article
- Keywords:
Ferrocene-terminated phenylethynyamine;
Cytochrome C;
Graphene,Sodium nitrite;
Electrocatalysis
- From:
Chinese Journal of Analytical Chemistry
2015;(3):325-332
- CountryChina
- Language:Chinese
-
Abstract:
Highly conjugated linear molecular wires are one of the basic elements for constructing molecular electronic devices. Among these conjugated compounds, ferrocene-terminated compounds as well as their derivatives have been widely studied because of their ideal electrochemical activity. Based on these, a new ferrocene-terminated phenylethynyaniline ( Fc-NH2 ) was synthesized by Sonogashira cross coupling reaction. The structure of the target compound was identified by infrared ( IR) , nuclear magnetic resonance ( NMR) , mass spectra ( MS) and cyclic voltammetry ( CV) . Combined the graphene-chitosan ( GH-CS) and Fc-NH2 , a new composite of GH-CS/Fc-NH2 was prepared and then used for immobilization of Cytc to prepare the GH-CS/Fc-NH2/Cytc/GCE. It was found from the CV result that a pair of peaks near-0. 2 V appeared which can be attributed to Cytc. The GH-CS/Fc-NH2/Cytc modified GCE showed good catalysis towards NaNO2 , and good linear relationship was found in the range of 1 ×10-7-1. 5 ×10-4 mol/L,and the determination limit was bellow 4×10-8 mol/L. Therefore, cytochrome c (Cytc) can be immobilized on the GH-CS/Fc-NH2 and the direct electron transfer can be realized between the electrode and solution and shows good prospect for detection of NaNO2 .
