With 3D-MPRAGE and DWI sequence evaluation of intraplaque hemorrhage before carotid artery stenting
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1002-1671.2014.11.006
   		
        
        	
        		- VernacularTitle:3D-MPRAGE 及 DWI 序列评价颈动脉支架术前斑块内出血的研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Bin YAO
			        		
			        		;
		        		
		        		
		        		
			        		Honglu SHI
			        		
			        		;
		        		
		        		
		        		
			        		Guangbin WANG
			        		
			        		;
		        		
		        		
		        		
			        		Li YANG
			        		
			        		;
		        		
		        		
		        		
			        		Xingyue ZHENG
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		carotid intraplaque hemorrhage;
			        		
			        		
			        		
				        		diffusion-weighted imaging;
			        		
			        		
			        		
				        		3D-MPRAGE;
			        		
			        		
			        		
				        		carotid artery stenting
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Practical Radiology
	            		
	            		 2014;(11):1798-1801
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To assess intraplaque hemorrhage before carotid artery stenting (CAS)by use of 3D-MPRAGE and DWI sequence.Methods Thirty-two symptomatic patients who had carotid artery plaque suspected by color Doppler ultrasonography and prepared for CAS underwent 3.0T carotid high-resolution MR scans,including regular sequence,T1-weighted gradient echo three-di-mensional magnetization prepared (3D-MPRAGE ) sequence,diffusion-weighted imaging (DWI ) sequences.According to 3D-MPRAGE sequence hemorrhage and non-hemorrhage groups were divided,and measured the mean ADC values of the two groups, hemorrhage and non-hemorrhage part in the hemorrhage group.Meanwhile preoperative cerebral hemorrhage group underwent brain DWI scans.Independent samples t-test analysis was utilized by SPSS V20.0 statistical software.Results High-resolution MRI dis-played 40 plaques,fourteen hemorrhagic plaques showed by 3D-MPRAGE sequence.The mean ADC values of hemorrhage and no-hemorrhage group were(1 233.5±283.5)× 10 -6 mm2/s,(1 688.9 ± 449.6)× 10 -6 mm2/s respectively,the difference of both was significant (t=3.43,P <0.05).The mean ADC values of hemorrhage and non-hemorrhage parts in the hemorrhage group mean ADC values were (934.0 ± 387.9)× 10-6 mm2/s,(1 313.9 ± 295.0)× 10-6 mm2/s respectively;the difference of both was statistically significant (t=2.92,P < 0.05 ).The difference of mean ADC values between non-hemorrhage part in the hemorrhage group and hemorrhage group was statistically significant (t=2.80,P <0.05).Conclusion 3D-MPRAGE and DWI sequences can be evaluated intraplaque hemorrhage before CAS,and provided a reliable basis for timely clinical interventions to prevent stroke.