The role of contrast-enhanced harmonic endoscopic ultrasonography in the diagnosis of pancreatic cancer
10.3760/cma.j.issn.1007-5232.2014.11.002
- VernacularTitle:谐波造影增强超声内镜在诊断胰腺癌中的作用
- Author:
Xiaojia HOU
;
Zhendong JIN
;
Jianwei ZHU
;
Xianbao ZHAN
;
Dong WANG
;
Can XU
;
Minmin ZHANG
;
Zhaoshen LI
- Publication Type:Journal Article
- Keywords:
Pancreatic neoplasms;
Endosonography;
Diagnosis;
Contrast enhanced harmonic
- From:
Chinese Journal of Digestive Endoscopy
2014;(11):624-627
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic accuracy of contrast-enhanced harmonic EUS (CH-EUS)for pancreatic cancer.Methods Patients with pancreatic occupying lesion underwent CH-EUS with ultrasonic contrast medium Sonovue.Pathological diagnoses by EUS-FNA or surgery and the follow-up results were made as the final diagnosis to evaluate the accuracy of CH-EUS for pancreatic cancer.Character-istics of CH-EUS in different pancreatic tumors were analysed.Results A total of 76 patients were en-rolled,with an average age of 53. 1 ±14. 2.Thirty-five were finally diagnosed as having pancreatic cancer, 21 local mass-type pancreatitis,10 pancreatic neuroendocrine tumor,6 cystadenoma,4 intraductal papillary mucinous neoplasm.Tumor diameter was 3. 4 ±1. 4 cm and there were 18 less than 2 cm.The sensitivity and specificity,positive and negative predictive value of CH-EUS for pancreatic cancer was 97. 1%, 92. 9%,91. 7% and 97. 5% respectively.The sensitivity was 100% combined with FNA.Conclusion CH-EUS is safe,convenient for pancreatic cancer with high accuracy and can be used as an additional diag-nostic method to EUS-FNA.
