Determination of plasma fibrin monomer and Dˉdimer in gerontal patients with malignant tumor and its clinical significance
10.3969/j.issn.1673-4130.2014.24.015
- VernacularTitle:老年恶性肿瘤患者血浆纤维蛋白单体和D-二聚体的测定及临床意义
- Author:
Guoli XIE
;
Chaoming ZHANG
;
Zeyou JIANG
- Publication Type:Journal Article
- Keywords:
plasma fibrin monomer;
D-dimer;
malignant tumor;
tumor thrombus
- From:
International Journal of Laboratory Medicine
2014;(24):3334-3335
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnosis and clinical application of fibrin monomer(FM)and D-dimer(D-D)in gerontal pa-tients with malignancy tumor.Methods FM and D-D were detected in 29 gerontal patients with malignant tumor,20 gerontal pa-tients with non-malignant tumor,24 gerontal healthy controls and 30 non-gerontal healthy controls by immunoturbidimetry(ITM). Results The testing results of FM and D-D in the tumor patients were significantly higher than those in the healthy controls(P <0.05).There was no statistical difference in FM and D-D between the gerontal patients with malignant tumor and the gerontal pa-tients with non malignant tumor(P >0.05).There was no statistical difference in FM between the gerontal healthy examination and non-gerontal healthy examination(P >0.05).There was statistical difference in D-D between the gerontal healthy examination and non-gerontal healthy examination (P < 0.05 ).Conclusion FM and D-D could be used as the indicators for diagnosing tumor thrombus in gerontal patients with tumor.However,D-D has meaningless in diagnosing tumor thrombus.In the diagnosis of tumor thrombus in gerontal patients with malignant tumor,the combination of FM and D-D should be needed.
