Clinical features of primary Sj(o)gren's syndrome with pulmonary hypertension

VernacularTitle:原发性干燥综合征合并肺动脉高压的临床特征
Author: Xuemei LI ; Qian WANG ; Yunyun FEI ; Mengtao LI ; Zhuang TIAN ; Yongtai LIU ; Xiaofeng ZENG
Publication Type:Journal Article
Keywords: Sjogren's syndrome; Pulmonary hypertension
From: Chinese Journal of General Practitioners 2014;13(9):770-773
CountryChina
Language:Chinese
Abstract: The clinical data were collected from medical record of 749 patients admitted into Peking Union Medical College Hospital from January 2008 to March 2013.They were diagnosed with primary Sj(o)gren's syndrome (PSS) at discharge.Clinical manifestations,laboratory results and outcomes were compared between PSS patients with pulmonary hypertension (PSS-PH) and those without (PSS-non PH).PSS-PH group had higher proportions of Renault phenomenon (36.8％ vs.20.0％,P =0.05),pericardial effusion (55.3％ vs.0.0％,P＜0.01),leukocytopenia (42.1％ vs.30.0％,P =0.03),elevated IgG level [(28.8 ±11.2) vs.(21.5 ±10.0) g/L,P=0.01] and hypothyroidism(34.2％ vs.12.5％,P=0.05) with significant significance.The PSS patients had leukocytopenia low thyroid function,rising IgG and pericardial effusion with pulmonary hypertension.