Diagnostic significance of combination of secretory leukocyte protease inhibitor (SLPI), interferon-γ(IFN-γ) and adenosine deaminase (ADA) for tuberculous pleural effusion
10.3969/j.issn.1006-5725.2014.10.015
- VernacularTitle:联合测定分泌型白细胞蛋白酶抑制因子、干扰素-γ和腺苷脱氨酶在结核性胸腔积液中的诊断意义
- Author:
Yanbin WU
;
Cong WU
;
Jinliang KONG
;
Shuangqi CAI
;
Tingmei FENG
;
Huasong LU
;
Xiangdong LIANG
- Publication Type:Journal Article
- Keywords:
Tuberculous pleural effusion;
Secretory leukocyte protease inhibitor;
Interferon-γ;
Aden-osine deaminase
- From:
The Journal of Practical Medicine
2014;(10):1566-1569
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the diagnostic significance of pleural SLPI,IFN-γ and ADA for differenti-ating TPE from pleural effusions with the other etiologies. Methods Pleural effusion samples were obtained from 93 patients who were divided into the following groups: tuberculous pleural effusion,malignant pleural effusion, bacterial pleural effusion and transudative pleural effusion. The pleural effusion and/or serum levels of SLPI , IFN-γand ADA were determined. Results 1.The concentrations of SLPI, IFN-γand ADA in tuberculous pleural effusion was higher than that in malignant group, bacterial group and transudative group. 2. The diagnostic value of SLPI, IFN-γor ADA for the diagnosis of tuberculous PE is high respectively. The combinations of SLPI, IFN-γand/or ADA gained the more valuable diagnostic performance. Conclusion Pleural SLPI, IFN-γand ADA may be helpful for the differential diagnosis of tuberculous pleural effusion and the other pleural effusion. The combinations of SLPI or/and IFN-γor/and ADA further increased diagnostic value.
