Research progress on anti-tumor metastasis of cryptotanshinone
10.3969/j.issn.1001-1978.2014.07.002
- VernacularTitle:隐丹参酮抗肿瘤转移的研究进展
- Author:
Huan YE
;
Junshan RUAN
;
Shaoming WANG
- Publication Type:Journal Article
- Keywords:
cryptotanshinone;
tumor metastasis;
integrin;
ap-optosis;
proliferation inhibition;
invasion
- From:
Chinese Pharmacological Bulletin
2014;(7):893-896
- CountryChina
- Language:Chinese
-
Abstract:
Cryptotanshinone (CPT)is a major fat-soluble ingre-dient in Salvia,which is a traditional blood-activating and stasis-dissolving drug.CPT has been gradually concerned,because it has a remarkable therapeutic effect on cardiovascular diseases, cancer and neurodegenerative diseases.A large number of exper-imental and clinical studies have shown that CPT can primarily inhibit tumor cell′s proliferation,angiogenesis,invasion and ad-hesion and induce apoptosis.Thus to some extent,it hinders in-vasion of tumor cell and prevents the distant metastasis.This pa-per focuses on the anti-tumor metastasis of CPT.
