Risk factors of free wall rupture after acute ST-segment elevation myocardial infarction
10.3969/j.issn.1004-8812.2014.05.007
- VernacularTitle:急性ST段抬高心肌梗死患者发生心室游离壁破裂的危险因素分析
- Author:
Chengyi XU
;
Lei HE
;
Chengwei LIU
;
Jinguo LU
;
Xi SU
- Publication Type:Journal Article
- Keywords:
Acute ST-segment elevation myocardial infarction;
Free wall rupture;
Thrombolytic therapy;
Primary percutaneous coronary intervention
- From:
Chinese Journal of Interventional Cardiology
2014;(5):304-307
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the risk factors of free wall rupture (FWR) in acute ST-segment elevation myocardial infarction (STEMI) patients. Methods We retrospectively reviewed all patients (n=1247) with STEMI hospitalized in CCU from January 2005 to July 2010. Results FWR occurred in 29 patients(2.3%). Of these 1247 patients, 128 (10.2%) patients received thrombolytic therapy, 623 (50.0%) patients underwent primary PCI. Compared to No-FWR group, FWR group has signiifcant differences in age (62.4±6.4 y vs. 66.6±8.3 y, P<0.05), hypertenion (29.7%vs. 21.8%, P>0.05), diabetes mellitu (55.2%vs. 23.5%, P=0.022), presence of heart failure on admission (Killip≥Ⅱ) ( 16.4%vs. 34.0%, P<0.05), Peak value of hCRP[20.33 (15.02, 81.25) vs. 43.35 (16.56, 126.78)], no-history of pervious MI (10.3%vs. 18.4%, P=0.018). Multivariate logistic regression showed that age (≥70 years old), Killip≥Ⅱ, hCRP ( > 100 mg/L) and thrombolytic therapy were independent risk factors of FWR. Conclusions STEMI patients with advanced age, Killip≥Ⅱ, hCRP and thrombolytic therapy were more vulnerable of FWR.
