The value of gemstone spectral CT imaging in characterizing the benign and malignant solitary pulmonary nodules
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1006-9801.2014.05.002
   		
        
        	
        		- VernacularTitle:宝石能谱CT在孤立性肺结节鉴别诊断中的价值
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Qi LIU
			        		
			        		;
		        		
		        		
		        		
			        		Xuting ZHANG
			        		
			        		;
		        		
		        		
		        		
			        		Hongxing JIN
			        		
			        		;
		        		
		        		
		        		
			        		Jiwei REN
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Solitary pulmonary nodules;
			        		
			        		
			        		
				        		CT spectral imaging;
			        		
			        		
			        		
				        		Diagnosis,differential
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Cancer Research and Clinic
	            		
	            		 2014;26(5):294-297
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To explore the value of gemstone spectral imaging (GSI) with single source dual-energy CT in characterizing the benign and malignant solitary pulmonary nodules (SPN).Methods Totally 32 patients with SPN underwent phaseⅢ enhanced CT scan using single source dual-energy CT by GSI mode.Three types of images were reconstructed for analysis:the water concentration (WC),iodine concentration (IC) and normalized iodine concentration (NIC).Results The IC of lung squamous cell carcinoma lung adenocarcinoma,hamartoma,sclerosing hemangioma,inflammatory pseudotumor were (11.66± 2.72) μg/ml,(12.36±2.97) μg/ml,(10.20±3.11) μg/ml,(16.58±3.58) μg/ml,(21.67±3.76) μg/ml,the IC of lung adenocarcinoma and lung squamous cell carcinoma had no difference (P > 0.05),there were significant differences in the value of iodine material between other nodules (all P < 0.05).The WC of lung adenocarcinoma,lung squamous cell carcinoma,hamartoma,sclerosing hemangioma,inflammatory pseudotumor were (1 021.31±13.83) μg/ml,(1 027.98±12.53) μg/ml,(1 003.42±13.67) μg/ml,(1 029.61±12.06) μg/ml,(1 051.61±13.81) μg/ml,there was no significant difference in the value of water material between nodules (all P > 0.05).Conclusion The spectral CT imaging may be helpful for characterizing the pathological type of SPN.