Role of REG4 in gastrointestinal carcinoma
10.3760/cma.j.issn.1673-4203.2014.07.016
- VernacularTitle:REG4在胃肠道肿瘤中的研究进展
- Author:
Xingwu ZHU
;
Chongzhi ZHOU
- Publication Type:Journal Article
- Keywords:
REG4 gene;
Stomach neoplasms;
Intestinal neoplasms;
Prognosis
- From:
International Journal of Surgery
2014;41(7):480-483
- CountryChina
- Language:Chinese
-
Abstract:
REG4,as a member of regenerating gene family,involves in proliferation and differentiation of gastrointestinal tract cells.Recent studies have shown that REG4 gene expression is upregulated in gastrointestinal cancer,pancreatic cancer,gallbladder cancer and prostate cancer,and associated with tumorigenesis,metastasis and poor prognosis of these carcinomas.Further studies have indicated that not only does REG4 play an important role in the diagnosis of gastrointestinal carcinoma,but also is closely linked with the effects of radiotherapy and chemotherapy.
