Interventional effects of emodin on transforming growth factor-beta1/integrin-linked kinase signal way in interleukin-1beta-induced transdifferentiation of rat tubular epithelial-myofibroblasts.
- Author:
Tingfang CHEN
;
Ming CHEN
;
Jianhua QIN
;
Mingyong WANG
- Publication Type:Journal Article
- From:
Journal of Integrative Medicine
2009;7(1):59-64
- CountryChina
- Language:Chinese
-
Abstract:
To study the effects of transforming growth factor-beta1/integrin-linked kinase (TGF-beta1/ILK) signal way in interleukin-1beta (IL-1beta)-induced rat tubular epithelial-myofibroblast transdifferentiation (TEMT), and to investigate whether emodin inhibits IL-1beta-induced TEMT through the TGF-beta1/ILK signal way-dependent mechanism.
