Analysis of distribution characteristics of serum hepatitis B virus markers of population in hospital
10.3969/j.issn.1673-4130.2014.10.013
- VernacularTitle:医院人群的血清乙型肝炎病毒标志物分布特征的分析
- Author:
Zian WU
;
Man LI
;
Ning XU
;
Xianli PENG
;
Zhenjie LIU
;
Yongjian CAO
;
Wenjun HE
- Publication Type:Journal Article
- Keywords:
hepatitis B virus;
biological markers;
hospital
- From:
International Journal of Laboratory Medicine
2014;(10):1263-1265
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution characteristics of serum hepatitis B virus (HBV) markers of population in hospital and to provide the basis for prevention and control of virus B hepatitis .Methods 11 210 people in hospital who had accepted HBV serological testing were enrolled ,and were divided into >0 -25-year old group(n=3 553) and >25 -50-year old group(n=7 651) according to their ages .Enzyme-linked Immunosorbent Assay(ELISA) and Roche Cobas E601 Automatic Electro-chemiluminescence immunoassay analyzer were employed to detect serum HBV surface antigen (HBsAg ) ,anti-HBV surface anti-body(HBsAb) ,HBV e antigen(HBeAg) ,anti-HBV e antibody(HBeAb) and anti-HBV core antibody(HBcAb) .Results HBsAg positive rates of subjects in > 0 -25-year old group and > 25 -50-year old group were 16 .16% and 21 .19% ,respectively .The overall positive rates of HBsAg and HBsAb and full-negative rate were 19 .59% (2 195/11 204) ,37 .02% (4 148/11 204) and 11 .84% (1 327/11 204) ,respectively .Conclusion Distribution characteristics of HBV markers of population in hospital may pro-vide a reliable basis for taking effective protective and control measures against virus B hepatitis .
