Study on chronotropic response in coronary disease with percutaneous coronary intervention
10.3760/cma.j.issn.1008-1372.2014.04.013
- VernacularTitle:介入治疗前后冠心病患者心脏变时性研究
- Author:
Zujin LIN
;
Haipeng CAI
;
Caiyun WU
;
Jiang CHEN
;
Hongwei PAN
- Publication Type:Journal Article
- Keywords:
Coronary disease/therapy;
Heart;
Angioplasty,transluminal,percutaneous coronary
- From:
Journal of Chinese Physician
2014;(4):471-474
- CountryChina
- Language:Chinese
-
Abstract:
Objecitve To investigate the changes of chronotropic response before and after percutaneous coronary intervention ( PCI)in patients with coronary disease .Methods A total of 339 patients with coronary disease was included in this study .All sub-jects underwent treadmill exercise test and coronary angiogram , and some patients underwent PCI if necessary .The parameters of chro-notropic response were recorded and analyzed , including ratio of the highest to predicted heart rates ( rHR) ,chronotropic response in-dex ( CRI) , and heart rate reserve ( HRR) .After coronary angiogram , the score of gensin was recorded and analyzed .Results There was significant difference in the parameter of CRI between unstable angina pectoris and silent myocardial ischemia groups ( P <0.05 ) , CRI were 0.80 ±0.11 and 0.89 ±0.07 , respectively .After coronary angiogram and PCI , there were significant differences in the parameters of rHR, CRI, and HRR between pre-therapy and post-treatment ( t =2.440, 1.977, 2.529, all P <0.05).A nega-tive correlation was found between the parameters of rHR , CRI, and HRR and the score of Gensin ( r =-0.686 , -0.673 , and-0.672, all P <0.05).The significant difference in rHR, CRI, and HRR existed between the groups of <20 and >40 ( t =2.567, 2.223, 2.062, all P <0.05).Conclusions Parameters (rHR, CRI, and HRR) had important clinical values in evaluating the changes of chronotropic response before and after PCI in patients with coronary disease with a negative correlation with the score of Gensin.
