Analysis on the distribution of pathogens in intensive care units and their drug resistance
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.1673-4130.2014.09.022
   		
        
        	
        		- VernacularTitle:重症监护病房病原菌分布及其耐药情况分析
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yanjun LI
			        		
			        		;
		        		
		        		
		        		
			        		Qiangyuan ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Xiuhong HAO
			        		
			        		;
		        		
		        		
		        		
			        		Yanghui QIAN
			        		
			        		;
		        		
		        		
		        		
			        		Yiwei DING
			        		
			        		;
		        		
		        		
		        		
			        		Xiaoyan LI
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		intensive care units;
			        		
			        		
			        		
				        		pathogens;
			        		
			        		
			        		
				        		drug resistance
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			International Journal of Laboratory Medicine
	            		
	            		 2014;(9):1140-1142
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To investigate the distribution of pathogens in intensive care units (ICU ) and their drug resistance . Methods 668 strains of pathogens isolated from specimens from ICU were collected .VITEK 2 Compact automated microbial iden-tification and susceptibility analyzer was utilized to conduct the antimicrobial susceptibility tests .Kirby-Bauer disk diffusion suscep-tibility test(K-B) was employed to conduct the antimicrobial susceptibility test for Gram-negative bacteria cefoperazone/sulbactam . Results 668 strains of pathogens were derived from sputum [434 (65 .0% )] ,blood[83(12 .0% )] ,urine[88(13 .0% )] ,drainage [14(2 .0% )] ,secretions[14(2 .0% )] and other[35(5 .2% )] .Acinetobacter baumannii was the major detected pathogen in Gram-negative bacteria and the resistance rates were over 50% toward other drug excepting levofloxacin ,sulfamethoxazole and amikacin . Staphylococcus Staphylococcus was the major detected pathogen in Gram-positive bacteria and it showed good sensitivity toward ni-trofurantoin ,quinupristin/dalfopristin ,tigecycline and vancomycin .Candida albicans demonstrated the highest detection rate in fun-gi .Conclusion ICU pathogens have drug resistance in serious condition ,and pathogens and drug resistance monitoring should be strengthened .