Relevance of bisphenol A and polycystic ovary syndrome

VernacularTitle:血清双酚A水平与多囊卵巢综合征相关性的初步研究
Author: Jianye FANG ; Jing YANG ; Tailang YIN ; Nan YU ; Youmin MO ; Xing JIANG
Publication Type:Journal Article
Keywords: Bisphenol A; Polycystic ovary syndrome
From: Chinese Journal of General Practitioners 2013;12(11):905-908
CountryChina
Language:Chinese
Abstract: To explore the relationship and possible mechanism of reproductive function of bisphenol A (BPA) with polycystic ovary syndrome (PCOS).Serum specimens were collected from 43 PCOS patients and 37 healthy women.And the level of BPA was detected by enzyme-linked immunosorbent assay (ELISA).The serum level of BPA in PCOS were significantly higher than that in the control group.And the inter-group difference was significant (P ＜ 0.05).The patient level of BPA was positively related with obesity and basic luteinizing hormone (LH) (P ＜ 0.05).In the PCOS group,no significant correlation existed between hyperandrogenemia and non-hyperandrogenemia (P ＞ 0.05).Although no difference existed between insulin and non-insulin resistance,the level of BPA in insulin resistance group was lower than in non-insulin resistance group.A higher level of BPA may be associated with obesity and basic LH in PCOS.