Peri-operative treatment for total hip replacement in patients with hepatic cirrhosis
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3969/j.issn.2095-4344.2013.52.005
   		
        
        	
        		- VernacularTitle:人工髋关节置换肝硬化患者围置换期的处理
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Jie XU
			        		
			        		;
		        		
		        		
		        		
			        		Jing HUANG
			        		
			        		;
		        		
		        		
		        		
			        		Ruofan MA
			        		
			        		;
		        		
		        		
		        		
			        		Deng LI
			        		
			        		;
		        		
		        		
		        		
			        		Zhiqing CAI
			        		
			        		;
		        		
		        		
		        		
			        		Liangping LI
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		hepatic cirrhosis;
			        		
			        		
			        		
				        		arthroplasty,replacement;
			        		
			        		
			        		
				        		hepatic inadequacy;
			        		
			        		
			        		
				        		albumin
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Tissue Engineering Research
	            		
	            		 2013;(52):8967-8973
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	BACKGROUND:Hepatic cirrhosis may adversely affect the outcome of major orthopedic surgery, such as total hip arthroplasty. Peri-operative treatment is the chal enge for al orthopedic surgeons. 
 OBJECTIVE:To analyze the safety and feasibility of hip replacement surgeries in patients with hepatic cirrhosis. 
 METHODS:Thirteen patients with hepatic cirrhosis that underwent hip replacement were retrospectively analyzed to evaluate the treatments and their efficacy before and after replacement. 
 RESULTS AND CONCLUSION:Al 13 surgeries were successful y performed. Al cases were fol owed up for more than five months and were graded according to Child-Pugh Criteria for hepatic functional reserve preoperatively and postoperatively. Five cases of the seven preoperative grade A cases preserved grade A postoperatively during a two-week observation, while another two cases rose to grade B and needed hepatic conservation treatment before discharge. Two cases of the six preoperative grade B cases rose to grade C with developed jaundice and ascites. Of the two, one even suffered a complication of upper gastrointestinal hemorrhage 5 days after surgery. Somatostatin and proton pump inhibitors were administered to stop bleeding. Al cases gained a satisfying recovery. Harris hip score at fol ow-up showed favorable hip function. Hip replacement is safe and feasible for patients with hepatic cirrhosis when ful evaluation of hepatic function and appropriate perioperative management are ensured.