Relationship between TMPRSS4 and tumor invasion and metastasis
10.3760/cma.j.issn.1673-4203.2013.07.015
- VernacularTitle:TMPRSS4与肿瘤侵袭转移的关系
- Author:
Yuxiang WANG
;
Xinyang HE
;
Wei LIANG
;
Hanhui YAO
;
Chuanhai ZHANG
;
Jiajia GUAN
- Publication Type:Journal Article
- Keywords:
TMPRSS4;
EMT;
Invasion;
Neoplasm metastasis;
Biology;
Serine proteases
- From:
International Journal of Surgery
2013;40(7):478-481
- CountryChina
- Language:Chinese
-
Abstract:
Type Ⅱ transmembrane serine proteases 4 (TMPRSS4) is a novel type Ⅱ transmembrane serine protease.Present study showed that its expression was related with tumor invasion and metastasis,although its oncogenic significance and molecular mechanisms are still unknown.In this review,the author try to introduce its structure,biological function and mechanism in tumor invasion and metastasis.
