Analgesic efficacy of methylene blue with ropivacaine on anorectal disease postoperation
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1671-7368.2013.04.019
   		
        
        	
        		- VernacularTitle:罗哌卡因联合亚甲蓝对肛肠疾病术后疼痛的疗效分析
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yonghui SU
			        		
			        		;
		        		
		        		
		        		
			        		Bingzong HOU
			        		
			        		;
		        		
		        		
		        		
			        		Juyuan BU
			        		
			        		;
		        		
		        		
		        		
			        		Xiaoling LI
			        		
			        		;
		        		
		        		
		        		
			        		Yingbin JIA
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Anus diseases;
			        		
			        		
			        		
				        		Methylene blue
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of General Practitioners
	            		
	            		 2013;12(4):290-291
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Between January 2011 and December 2011,86 patients undergoing operation for anorectal disease were randomized in a double-blind manner to receive a mixed injection of methylene blue,ropivacaine and sodium chloride (observation group,n =43) or traditional analgesic methods (control group,n =43).Patients in observation group had less visual analog scale (VAS) scores of pain at 6-48 h postoperation than control group (P <0.05).The scores had no significant difference at 72 h postoperation between two groups (P > 0.05).The total postoperative complications (8,19%) and hospitalization duration [(5.3 ± 2.2) days] in observation group were significantly less than those [15,35 % and (6.4 ±1.7) days] in control group (P < 0.05).A mixed injection of methylene blue and ropivacaine intraoperatively can relieve the postoperative pain of patients with anorectal disease and reduce the incidence of postoperative complications and the duration of hospitalization.