Analysis of high risk factors of liver metastasis in patients with postoperative colorectal cancer

VernacularTitle:大肠癌术后肝转移高危因素研究
Author: Yue JIANG ; Aman WANG ; Jie ZHANG ; Liying BAN ; Tao ZHOU
Publication Type:Journal Article
Keywords: Colorectal neoplasms; Neoplasm metastasis; Liver; Risk factors
From: Journal of International Oncology 2013;(5):392-395
CountryChina
Language:Chinese
Abstract: Objective To screen the risk factors of liver metastasis in patients with postoperative colorectal cancer and to set up a mathematic model.Methods One hundred and sixty-eight patients received radical surgery were retrospectively analyzed.Logistics model regression was used to identify the risk factors and ROC test to complete a mathematic model.Results The 3 and 5-year incidence rate of liver metastasis was 25.0％ and 33.3％,respectively.The risk factors of liver metastasis were lymph node metastasis (LNM),tumor invasive depth (TID),histological grading (G) and preoperative serum tumor markers (PSMs).The mathematic model was:logit (P) =-0.931 + 0.973 × LNM + 0.302 x TID + 0.637 x G + 0.042 x PSMs.Conclusion The risk factors of liver metastasis were LNM,TID,G and PSMs,and the mathematic model could be set up.