Detection of S-100 protein in laryngeal carcinoma
10.3969/j.issn.1001-1781.2001.03.004
- VernacularTitle:喉癌组织S-100蛋白的检测
- Author:
Sunhong HU
;
Lei ZHANG
;
Sanli WEN
;
Dejian LI
- Publication Type:Journal Article
- From:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
2001;(3):110-111
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the relationship between S-100 protein and prognosis of laryngeal carcinoma.Method:S-100 protein was observed by immunohistochemical methods using anti-S-100 protein antibody in 68 laryngeal carcinoma and 21 non-cancer laryngeal tissues.Result:The result showed that S-100 protein positive were found 43(63.24%)in 68 laryngeal carcinoma.S-100 protein positive cells were interspersed among the tumor cells and in the stroma.S-100 protein were rare in non-cancer laryngeal tissues.The five-year survival rate in patients with S-100 protein positive was significantly higher than that in patients with S-100 protein negative.Conclusion:Our result indicated that the detection of S-100 protein is of value for the prognostic analysis in patients with laryngeal carcinoma.
