Lesion Conspicuity of Hypoxic-ischemic Encephalopathy in Neonates: a Comparison of Various Magnetic Resonance Imaging Sequences.
10.3348/jkrs.2008.58.1.97
- Author:
Dae Wook YEH
1
;
Hak Jin KIM
;
Tae Un KIM
;
Sang Ook NAM
;
Su Eun PARK
Author Information
1. Department of Diagnostic Radiology, Pusan National University Hospital, Busan, South Korea. hakjink@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Infant, newborn;
Hypoxia-ischemia, brain;
Magnetic resonance (MR)
- MeSH:
Brain;
Brain Stem;
Cerebral Cortex;
European Continental Ancestry Group;
Extremities;
Humans;
Hypoxia-Ischemia, Brain;
Infant, Newborn;
Internal Capsule;
Magnetic Resonance Imaging;
Magnetic Resonance Spectroscopy;
Magnetics;
Magnets;
Pyramidal Tracts;
Retrospective Studies
- From:Journal of the Korean Radiological Society
2008;58(1):97-104
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To determine which magnetic resonance (MR) imaging sequence demonstrates the highest lesion conspicuity for lesion detection in neonates with hypoxic-ischemic encephalopathy (HIE). MATERIALS AND METHODS: In 30 neonates with HIE, lesion conspicuity in different brain structures was retrospectively compared on T1-weighted images, T2-weighted images, fluid-attenuated inversion recovery images, and diffusion-weighted images (DWI). The brain structures were categorized as follows: cerebral cortex; cerebral white matter; deep gray matter; posterior limb of the internal capsule (PLIC); brain stem; and cerebellum. RESULTS: For the deep gray matter, T1-weighted imaging was superior to the other sequences in lesion detection of 9 of 14 patients (64.3%), whereas DWI was superior in only 4/14 patients (28.6%). For the cerebral cortex, T1- and DWI were similar in lesion conspicuity (5/13 patients and 6/13 patients, respectively). For the white matter, HIE lesions were most conspicuous on DWI in a majority of the study patients. Lesions were detected in the cerebral white matter in 16/20 patients (80.0%), lesions were detected in the PLIC in 11/12 patients (91.7%), lesions were detected in the corticospinal tract in the brain stem in 11/11 patients (100%) and lesions were detected in the cerebellar white matter in one patient (100%). CONCLUSION: In neonates with HIE, white matter lesions are most conspicuous on DWI, whereas gray matter lesions tend to have greater conspicuity on T1-weighted images than on the other MR sequences.
