Patients with both hepatocellular and chnlangiocarcinoma and their clinicopathological features

VernacularTitle:肝细胞-胆管细胞混合型肝癌的诊治进展
Author: Kaijian CHU ; Chongde LU ; Xiaoping YAO
Publication Type:Journal Article
Keywords: Combined hepatocellular and cholangiocarcinoma; Pathological diagnosis and classification; Clinical characteristics; Prognoses
From: Chinese Journal of Hepatobiliary Surgery 2012;18(7):561-563
CountryChina
Language:Chinese
Abstract: Combined hepatocellular and cholangiocarcinoma (HCC-CC) is a unique primary epithelial tumor of the liver classified by the WorldHealth Organization (WHO) as a tumor containing elements of both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC).The clinical diagnosis is established by histopathology and a firm pathological diagnosis from definitive evidence of HCC and CC differentiation.HCC-CC's clinical features tend to resemble hepatocellular carcinoma in regards to venous infiltration and like cholangiocarcinoma with respect to lymph node metastasis.To date,the biological behavior of HCC-CC remains ill-defined; however its prognosis seems to be worse than just HCC.Conversely,it is unclear whether the prognosis of HCC-CC is better than that of only ICC.This paper reviews recent studies on the clinicopathological behavior of HCC-CC.