Anti-tumor mechanism of CIK cells and research
10.3760/cma.j.issn.1673-422X.2012.05.008
- VernacularTitle:细胞因子诱导杀伤细胞的抗肿瘤机制及其应用研究
- Author:
Chunhua WANG
;
Yifu HE
;
Bing HU
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Killer cells;
Immunotherapy
- From:
Journal of International Oncology
2012;39(5):348-351
- CountryChina
- Language:Chinese
-
Abstract:
Cytokine-induced killer (CIK) cells are T lymphocytes which have natural killer cell activity and antitumor activity.It is found that CIK cells play an important role in killing tumor cells by secreting cytotoxic granules and cytokines,activating NKG2D receptor and regulating oncogene expression.CIK cells can not only kill the tumor cells,but also can improve immune system and the quality of life of patients.A large number of studies have shown that CIK treatment is a new mode of cancer treatment without obvious adverse reactions and can be widely applied in clinical treatment.
