Human cytomegalovirus infection concerned with carotid atherosclerosis
10.3760/cma.j.issn.1008-6315.2011.11.018
- VernacularTitle:人巨细胞病毒感染与颈动脉粥样硬化的关系
- Author:
Weiying DI
;
Fuping SHI
;
Liping LIU
;
Yanfei WANG
;
Guohua ZHANG
;
Tongkai LI
;
Dechao WANG
- Publication Type:Journal Article
- Keywords:
Cytomegalovirus infections;
Carotid artherosclerosis;
Human-cytomegalovirus-PP65 antigen
- From:
Clinical Medicine of China
2011;27(11):1176-1178
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the correlation of human cytomegalovirus infection with carotid atherosclerosis.Methods A total of 120 patients with carotid atherosclerosis and 140 healthy control patients were recruited for HCMV-PP65 antigen detection and Ultrasound examination.Results In carotid atherosclerosis and healthy patients,58.20％(71 cases)and 6.43％(9 cases)of the subjects were positive for HCMV-PP65 antigen(x2 =32.98,P ＜ 0.05).In carotid atherosclerosis group,69.01％(49 cases)of the patients with positive HCMV-PP65 antigen had instable plaques,while it was 47.06％(24 cases)in the patients with negative HCMV-PP65 antigen.The difference in the positivity of HCMV-PP65 between the two groups were significant(x2 =8.22,P ＜ 0.05).Conclusion Active infection of HCMV may be associated with Carotid Atherosclerosis and the plaques will be more instable.
