Preventive effects of rivaroxaban on the deep vein thrombosis after orthopedic surgery
10.3760/cma.j.issn.1673-4203.2011.11.018
- VernacularTitle:利伐沙班对骨科大手术后深静脉血栓预防作用的研究进展
- Author:
Hui TANG
;
Jinliang HUANG
;
Chuan LI
;
Yongqing XU
- Publication Type:Journal Article
- Keywords:
Rivaroxaban;
Deep vein thrombosis;
Enoxaparin
- From:
International Journal of Surgery
2011;38(11):778-781
- CountryChina
- Language:Chinese
-
Abstract:
The morbidity of deep vein thrombosis (DVT) after total hip replacement,total knee replacement or hip fractures surgery is high,and there is no effect way to prevent.Rivaroxaban is an oral,direct factor Xa inhibitor.The prevention effect of rivaroxaban to DVT after orthopedic surgery is stronger than enoxaparin.The view summarizes the mechanism,pharmacokinetics,interaction of drugs and the antithrombotic effect after orthopedic surgery.
