Analysis of the relationship between plasma D-dimer and hepatic functional reserve status in patients with hepatitis B
10.3760/cma.j.issn.1008-6706.2011.20.013
- VernacularTitle:乙型肝炎患者血浆D-二聚体水平与肝功能储备状态的关系
- Author:
Wenxue ZHANG
;
Li WANG
;
Li YU
;
Tilong DING
;
Yong MA
- Publication Type:Journal Article
- Keywords:
Hepatitis B;
Hepatic functional;
D-dimer
- From:
Chinese Journal of Primary Medicine and Pharmacy
2011;18(20):2762-2763
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the relationship between the level of plasma D-dimer(D-D) and hepatic functional reserve status in patients with hepatitis B (HB).Methods77 cases with HB were divided into two groups, hepatic function compensated group and hepatic function decompensated group.Plasma D-D, hepatic functional indexes and PT of all patients were detected.ResultsThe level of D-D in the hepatic function decompensated group was higher than that in the hepatic function compensated group(299.0 ± 498.5) μg/L vs (27.9 ± 34.0) μg/L(t =3.1, P ＜ 0.01).D-D negatively correlated with ALB and PA(r =-0.6,-0.6, all P ＜ 0.01), and positively correlated with TBIL and PT(r = 0.4,0.6, all P ＜ 0.01).ConclusionThe level of plasma D-D related with hepatic functional reserve status,and detecting the level of D-D could be helpful to estimate hepatic functional reserve and prognosis of patients with HB.
