Etiology and clinical features of 182 cases of erythroderma

VernacularTitle:182例红皮病病因与临床特征分析
Author: Kai LI ; Liuqing CHEN ; Guangyan YANG ; Jianjun XING ; Lingjuan SONG ; Qing LUO ; Jingfeng BAI ; Liang ZHANG ; Xianyu ZENG ; Xiaoyong ZHOU ; Yiqun DUAN
Publication Type:Journal Article
Keywords: Erythroderma; Prognosis
From: Chinese Journal of Dermatology 2011;44(11):786-788
CountryChina
Language:Chinese
Abstract: ObjectiveTo study the correlation between the etiology and clinical features of erythroderma.MethodsThe clinical data on 182 patients with erythroderma were retrospectively collected and analyzed.ResultsThe male-to-female ratio was 2.8 ∶ 1 and the average age at onset was 58.6 ± 14.6 years.Of the 182 cases,135 (74.2％) were due to pre-existing dermatoses,14 (7.7％) to drug reaction,8 (4.4％) to malignancies,while 25(13.7％) had no obvious precipitating factors.The most frequent triggering factor was systemic consumption of drugs(52 patients,28.6％ ),and glucocorticosteroid was the most prevalent causative drug.Seventy-six patients were followed up,recurrence was observed in 14 patients but not in 58 patients,and 5 patients died,2 patients with idiopathic erythroderma were finally diagnosed with mycosis fungoides (MF)after multiple skin biopsies.ConclusionsPre-existing dermatoses are the most frequent cause of erythroderma.Idiopathic erythroderma is liable to relapse,possibly associated with malignancies,and should be closely followed up.