Prevalence of toxoplasma, rubella virus, cytomegalovirus and herpes simplex virus infections among 3084 individuals with childbearing-age in Henan province
10.3760/cma.j.issn.1674-2397.2012.05.004
- VernacularTitle:河南省3084例育龄男女弓形虫、风疹病毒、巨细胞病毒、单纯疱疹病毒感染状况调查分析
- Author:
Wanhai WANG
;
Qingfang WANG
;
Jianli LI
;
Meifen WANG
;
Jiatian LIU
;
Yuanding MEI
;
Dongchun QIN
;
Liang MING
- Publication Type:Journal Article
- Keywords:
Infection;
Toxoplasma;
Rubella virus;
Cytomegalovirus;
Simplexvirus;
People of childbearing age;
Epidemiology
- From:
Chinese Journal of Clinical Infectious Diseases
2012;5(5):270-273
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prevalence of toxoplasma gondii (Tox),rubella virus (RV),cytomegalovirus (CMV) and herpes simplex virus (HSV) infections (TORCH infections) among childbearing-age population in Henan province.Methods Enzyme-linked immunosorbent assay (ELISA) was applied to detect plasma TORCH IgM and IgG among 3084 childbearing-age men and women from theFirst Affiliated Hospital of Zhengzhou University during July and September,2011.The positive rates of anti-TORCH antibodies were compared among the various age and gender groups by x2 test.Results The total positive rate of anti-TORCH IgM was 5.5％ (170/3084),in which the positive rate of anti-RV IgM was the highest (2.9％),followed by anti-HSV IgM (1.0％).Within positive rate of anti-TORCH IgG,anti-HSV IgG was the highest (90.4％),followed by anti-CMV IgG (89.7％),RV IgG (48.1％) and Tox IgG (0.7％).The positive rate of anti-TORCH IgM was the lowest in individuals aged ＞ 30-40 year old.With the age increasing,the positive rates of anti-Tox IgG,anti-CMV IgG and anti-HSV IgG increased,but the positive rate of anti-RV IgG decreased.Women had higher positive rates of anti-CMV IgG and antiHSV IgG than men (x2 =83.470 and 7.026,P ＜ 0.O1).Conclusions Current infection of TORCH exists in childbearing-age population of Henan province,and the positive rate of anti-RV IgG is low.It is recommended to screen for TORCH infection in childbearing-age men and women.
