Research progress of interleukin-32
10.3760/cma.j.issn.1673-422X.2012.09.008
- VernacularTitle:白细胞介素-32研究进展
- Author:
Songlin LI
;
Yuanqin YIN
- Publication Type:Journal Article
- Keywords:
Interleukin-32;
Transcription factors;
Death receptor
- From:
Journal of International Oncology
2012;39(9):669-671
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin-32 is a newly descovered cytokine. In vivo and in vitro studies show that it inhibits the proliferation and induces apoptosis of colon cancer and melanoma by inhibiting NF-κB and signaling and transcription activated factor 3 pathways.In addition,IL-32 suppresses tumor growth in different ways in chronic myelogenous leukemia,sarcoma and prostate cancer.
