A case of thyrotropin-secreting pituitary adenoma treated with long-acting octreotide formulation

VernacularTitle:长效奥曲肽治疗垂体促甲状腺激素瘤一例临床探讨
Author: Xiaoping CHEN ; Xin WANG ; Xiaoyan XING ; Yi LU ; Guangwei LI
Publication Type:Journal Article
Keywords: Pituitary neoplasms; Octreotide
From: Chinese Journal of General Practitioners 2011;10(8):581-583
CountryChina
Language:Chinese
Abstract: A 56-year-old man with 1-year history of palpitation, heat intolerance and sweating, was diagnosed as thyrotropin (TSH) -secreting pituitary adenoma based on the symptoms of hypermetabolism, enlarged thyroid gland, inappropriately increased serum TSH concomitantly elevated plasma thyroid hormones and a pituitary tumor demonstrated on magnetic resonance imaging. Long-acting octreotide formulation was administered at a dose of 20 mg intramuscularly. Tumor volume shrinkage and improvement of thyroid function was achieved after a single drug injection; and the thyroid function returned to normal in 28 days. It is suggested that long-acting octreotide formulation might be used as a routine therapeutic approach prior to pituitary surgery, which may enhance the effectiveness of surgery and postoperative recovery.