Study on binding capacity of low-density lipoprotein to its receptors in diabetic patients

VernacularTitle:糖尿病患者低密度脂蛋白与内皮细胞受体结合的研究
Author: Dongping LIN ; Lizhen YANG ; Xiaohua PAN ; Boren JIANG ; Yuyu GUO ; Hui ZHU ; Tao LEI ; Yinli LU
Publication Type:Journal Article
Keywords: Diabetes mellitus; Lipoproteins; Low density; Receptor binding
From: Chinese Journal of Endocrinology and Metabolism 2011;27(5):418-419
CountryChina
Language:Chinese
Abstract: The levels of low-density lipoprotein(LDL)glycation from control group,diabetic HbA1C < 7.0%,and HbA1C>7.0% groups were(17.7±2.31),(34.29±5.73),and(48.79±7.82)Glycogroups/LDL by fluorimetry.The LDL binding to its receptor in three groups were(37.65±5.20),(27.36±4.34),and(15.07± 2.23)ng/mg cell protein measured by enzyme-linked immunoreceptor assay.The glycated levels in two diabetic groups were higher than that in control group,and higher in HbA1C>7.0% group than in HbA1C<7.0% group(all P< 0.01).The results of LDL binding capacity to its receptor were just the opposite.