Study on the extracting method of salviae miltiorrhizae madix et rhizoma in Huoluo-Xiaoling granules

VernacularTitle:活络效灵颗粒中丹参的提取工艺研究
Author: Chao WANG ; Yuanyan LIU ; Qing LI ; Lei XIA ; Zhiqian SONG ; Chun WANG ; Yuna CAO ; Zheng WEI ; Linyan ZENG ; Zhenli LIU
Publication Type:Journal Article
Keywords: Huoluo-Xiaoling granules; Salviae Miltiorrhizae Madix et Rhizoma; Extraction method; Salvianolic acid B; Tanshinone ⅡA
From: International Journal of Traditional Chinese Medicine 2011;33(7):605-608
CountryChina
Language:Chinese
Abstract: Objective To optimize the extraction method of salviae miltiorrhizae madix et rhizoma in Huoluo-Xiaoling granules. Methods According to the contents of Salvianolic acid B and Tanshinone Ⅱ A, the extraction method was established by comparing different solvents (water and 70% ethanol)and extracting modes (compound extraction and single herb extraction). Then orthogonal design was used to determine the optimum extraction method. Results Considering the contents of salvianolic acid B and tanshinone Ⅱ A, 70% ethanol extract was better than water extract and compound extraction was better than single herb extraction.The optimum extraction condition was 70% ethanol in eight times of the herbs weight, extracted for 1h by 3times. Conclusion The extraction method was simple and stable.