Relationship between folic acid levels of cord blood and birth weight, hyaline membrane disease in newborns
10.3760/cma.j.issn.1673-4904.2011.09.002
- VernacularTitle:脐血叶酸水平与新生儿出生体重和肺透明膜病的关系
- Author:
Yaqin LI
;
Zhangbin YU
;
Shuping HAN
;
Yulin CHEN
;
Xiaoqi GU
;
Li SHA
;
Junxia JIN
;
Lubiao YAN
;
Xirong GUO
- Publication Type:Journal Article
- Keywords:
Fetal blood;
Folic acid;
Infant,newborn;
Birth weight;
Hyaline membrane disease
- From:
Chinese Journal of Postgraduates of Medicine
2011;34(9):4-7
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between folic acid levels of cord blood and birth weight, hyaline membrane disease in newborns. Methods Eighty-seven newborns were divided into premature infant group(42 cases) and term infant group(45 cases),intrauterine growth retardation group( 28cases) and control group (59 cases), hyaline membrane disease of premature infant group ( 13 cases) and premature infant control group(15 cases) according to the gestational age, birth weight, clinical manifestation and chest X-ray, respectively. Folic acid levels of cord blood were measured. Results The folic acid level of cord blood in premature infant group was lower than that in term infant group [(10.87 ±4.31) nmol/L vs.( 13.56 ± 5.07) nmol/L,P ＜0.05 ]. The folic acid level of cord blood in intrauterine growth retardation group was lower than that in control group [(11.01±4.29)nmol/L vs.( 14.87 ± 5.14)nmol/L,P＜0.05]. The folic acid level of cord blood in hyaline membrane disease of premature infant group was lower than that in premature infant control group [(9.15 ±4.02) nmol/L vs.(12.91±4.51) nmol/L,P＜0.05]. The positively correlation was found between the folic acid level of cord blood and birth weight in newborns (r =0.1825).Conclusion The folic acid level of cord blood is correlated with the occurrence of premature infants,intrauterine growth retardation and hyaline membrane disease in newborns.
