Dual antiplatelet therapy after cervical artery stenting: how long is appropriate?
10.3760/cma.j.issn.1673-4165.2011.04.005
- VernacularTitle:颈部动脉支架置入术后双联抗血小板治疗:多久合适?
- Author:
Qian LI
;
Guangqin LI
;
Youdong WEI
;
Wanfu WU
;
Xinyue QIN
- Publication Type:Journal Article
- Keywords:
Carotid stenosis;
Atherosclerosis;
Stents;
Platelet aggregation inhibitors;
Aspirin;
Clopidogrel
- From:
International Journal of Cerebrovascular Diseases
2011;19(4):261-264
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of dual antiplatelet therapy at different time after cervical artery stenting and to investigate the reasonable time for dual antiplatelet therapy. Methods Sixty-six patients with symptomatic cervical artery artery stenosis ＞50% or asymptomatic stenosis ＞70% performed stenting under local anesthesia. They were randomly allocated into dual antiplatelet therapy (aspirin + clopidogrel) for 1 month and for 3-month groups after procedure, and then they began to take aspirin for a long time. The complications, vascular events, and the incidence of restenosis were observed respectively. Results There were no vascular events and death in both groups from 6 to 36 months after procedure. There was no significant difference in the incidence of complication and restenosis (9% vs. 6%, P = 0. 642). Conclusions There was no significant difference in the efficacy of aspirin + clopidogrel treatment after cervical artery stenting between 1 month and 3 months. One month dual antiplatelet therapy may be appropriate, but large-scale randomized controlled trials are needed to confirm it.
