Anti-thrombotic， Choleretic and Anti-ulcerous Actions of Rhizoma Ligustici
- VernacularTitle:藁本的抗血栓形成、利胆和抗溃疡作用
- Author:
Mingfa ZHANG
;
Yaqin SHEN
;
Ziping ZHU
;
Hongwu WANG
- Publication Type:Journal Article
- From:
China Pharmacy
2001;12(6):329-330
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE： To study the anti-thrombotic， choleretic and anti-ulcerous actions of Rhizoma Ligustici.METHODS： Experiments were carried out on conventional models of choleresis and ulceration， and on a thrombotic model of using direct current continuously to stimulate the unilateral carotid artery of anesthetic rat.RESULTS： Alcoholic extract of Rhizoma Ligustici 3g herb/kg and 10g herb/kg id or ig， increased choleresis and prolonged the time for arterial thrombosis induced by electric stimulation in rats， but did not prolonged coagulative time， PT and KPTT.The extract 5g herb/kg and 15g herb/kg ig， inhibited the formation of gastric ulcers induced by water immersion， stress， HCl and indomethacin-alcohol in mice.CONCLUSION： Rhizoma Ligustici has anti-thrombotic choleretic and anti-ulcerous actions.
