HIV Vaccine-Challenges and Opportunities
- Author:
Xin MA
;
Caijun SUN
;
Feng LI
;
Ling CHEN
- Publication Type:Journal Article
- Keywords:
Neutralizing antibody;
Cellular immune;
Protective immunity;
Immunogen;
Efficacy studies
- From:
Virologica Sinica
2007;22(6):486-492
- CountryChina
- Language:Chinese
-
Abstract:
The need for an efficacious HIV/AIDS vaccine remains the highest priority of the world HIV/AIDS agenda. The generation of an efficacious HIV/AIDS vaccine proves an enormous scientific challenge. This article reviews the neutralizing antibody problem, elusive immune protection, immunogen design, pre-existing anti-vector immunity and design of phase 3 vaccine trials and the challenges and opportunities in development of HIV/AIDS vaccine are discussed.
