The effects of glucosamine and chondroitin sulfate compound tablet on anti-inflammatory and analgesic
- VernacularTitle:氨基葡萄糖与硫酸软骨素复方片的抗炎、镇痛作用
- Author:
Gang HAN
;
Haizhong YUAN
;
Yue DONG
;
Guanyu ZHAI
;
Ying FAN
- Publication Type:Journal Article
- Keywords:
glucosamine;
chondroitin sulfate;
anti-inflammatory;
analgesic;
compound tablet
- From:
Chinese Journal of Biochemical Pharmaceutics
2010;31(1):39-41
- CountryChina
- Language:Chinese
-
Abstract:
Purpose The glucosamine and chondroitin compound tablets were prepared. The anti-inflammatory and analgesic effects of glucosamine and chondrotin compound tablets were investigated. Methods The proportion of glucosamine and chondroitin was 5:4 to prepare compound tablets. The anti-inflammatory effect was investigated with carrageen-induced rats paw edema and cotton granuloma in rats. The analgesic effect was investigated using the pain models of mice which were induced by 0.6% acetic acid. Results Compared with control group the degree of paw edema in the low, middle and high dose group was decreased ( P < 0.05). Fourtreatment groups compared with control group respectively at the weight of granuloma were also markedly reduced ( P < 0.05) and the writhing number of mice induced by acetic acid was decreased ( P < 0.05 ) . Conclusion glucosamine and chondroitin compound tablets have anti-inflammatory effect and analgesic effect on models induced by acetic acid.
