A Case of Pseudomelanosis Duodeni.
- Author:
Sang Kyun YU
1
;
Young Kul JUNG
;
Jeong Han KIM
;
Ji Yeon LEE
;
Kiho PARK
;
Kyoung Oh KIM
;
Hyung Joon YIM
;
Jin Yong KIM
;
Jong Jae PARK
;
Jae Seon KIM
;
Young Tae BAK
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. drbakyt@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Duodenum;
Pseudomelanosis;
Antihypertensive agents;
Iron supplement
- MeSH:
Aged;
Anemia, Iron-Deficiency;
Antihypertensive Agents;
Biopsy;
Depression;
Duodenum;
Endoscopy, Gastrointestinal;
Female;
Heart Failure;
Humans;
Hypertension;
Iron;
Kidney Failure, Chronic;
Macrophages;
Mucous Membrane
- From:Korean Journal of Gastrointestinal Endoscopy
2004;28(1):39-42
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pseudomelanosis duodeni is a rare benign condition in which dark pigments accumulate in macrophages located in the lamina propria of the duodenal mucosa. Most reported cases had hypertension with or without chronic renal failure, and were taking antihypertensive agents and iron supplements. Therefore, it has been assumed that pseudomelanosis duodeni is associated with these medications. Our case was a 77 year-old female patient diagnosed as having hypertension, congestive heart failure, iron deficiency anemia, and depression, who had been treated with antihypertensive agents and iron supplement. Upper gastrointestinal endoscopy revealed many tiny discrete dark macules scattered throughout the first and second portions of the duodenum. Endoscopic mucosal biopsy disclosed macrophages with Prussian blue and Fontana-Masson stain positive pigments, which suggested that the nature of pigment was iron sulfide.
