Therapeutic efficacy of the nanometer high-frequency square pulse light technology targeting kidney cancer
- VernacularTitle:纳米-高频脉冲光技术靶向治疗肾癌的实验研究
- Author:
Lijun CHEN
;
Jianyong SUN
;
Li ZHAO
;
Nan QU
;
Yuanbin XU
;
Zhenpeng SUN
;
Xuechao LI
- Publication Type:Journal Article
- Keywords:
Kidney neoplasms;
Carcinoma;
Nanometer;
High-frequency square pulse light
- From:
Chinese Journal of Urology
2008;29(z1):9-11
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the therapeutic efficacy of nanometer high-frequency square pulse light technology targeting kidney cancer.Methods Fifty BALB/c nude mice were vaccinated with human ACHN cell line and randomly divided into 1 control group and 4 therapeutic groups.The 4 therapeutic groups were cured with high-frequency square pulse light and nanometer high-frequency square pulse light.The treatment cycle was 4 weeks.The tumor growth condition and tumor-repres-sion change were observed and compared.Results The tumor volumes of the control group in-creased obviously,whereas the tumor volumes of the therapeutic groups decreased obviously or in-creased gently.The mean tumor volume and the tumor growth curve of the therapeutic groups were significantly lower than those of the control group(P＜0.05),but there was no significant difference between the therapeutic efficacy of the kidney cancer using high-frequency square pulse light and nanometer high-frequency square pulse light(P＞0.05).Synteresis of kidney carcinogenesis experiments results indicated that using high-frequency square pulse light and nanometer high-frequency square Dulse light could prevent the production and development of the kidney cancer(P＜0.05),but the svnteresis efficacy of the 2 methods had no obvious difference(P＞0.05).Conclusion Using highfrequency square pulse light and nanometer high-frequency square pulse light can cure the kidney cancer and,to some extent,prevent the production and development of kidney cancer.
