Evaluation of intraventricular dyssynchrony in patients with coronary artery disease by two dimensional strain imaging
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1004-4477.2009.04.003
   		
        
        	
        		- VernacularTitle:超声斑点追踪二维应变对冠心病患者左心室同步性的研究
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yuhan WU
			        		
			        		;
		        		
		        		
		        		
			        		Youbin DENG
			        		
			        		;
		        		
		        		
		        		
			        		Runqing HUANG
			        		
			        		;
		        		
		        		
		        		
			        		Xiaojun BI
			        		
			        		;
		        		
		        		
		        		
			        		Rong LIU
			        		
			        		;
		        		
		        		
		        		
			        		Ceyao ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Ying ZHU
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Echocardiography;
			        		
			        		
			        		
				        		Coronary disease;
			        		
			        		
			        		
				        		Ventricular function,left;
			        		
			        		
			        		
				        		Two-dimensional strain
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Ultrasonography
	            		
	            		 2009;18(4):281-283
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To evaluate the dyssynchrony of left ventricle in patients with coronary artery disease(CAD) by two-dimensional strain echocardiography (2-DS). Methods The myocardium of left ventricle of 33 patients with CAD and 30 nomal controls were detected by 2-DS. The time from onset QRS complexes to peak systolic longitudinal strain(Ts) and the standard deviation of Ts of 18 left ventricular segments (Ts-SD)were measured. Results There were 168 segments whose flow was provided by coronary artery with stenosis≤75% ,210 segments whose flow was provided by coronary artery with stenosis 75 %. ①Ts was delayed significantly and Ts-SD was obviously higher in patients with stenosis≥75% when compared with the control group. ②Ts was delayed and Ts-SD was higher in patients with stenosis≥75% compared with those whose stenosis was ≤75%. ③There were no statistical differences in Ts and Ts-SD between the patients with stenosis ≤75% and the control group. ④When left ventricular systolic dyssynchrony was defined as Ts-SD≥33.0 ms, there were 22 patients with systolic dyssynchrony of all 26 patients whose coronary artery stenosis≥75%, there were no patient with systolic dyssynchrony of all 7 patients whose stenosis ≤75%. Conclusions Although there are no evident regional wall motion abnormalities by routine echocardiography,in patients with severe coronary artery stenosis,2-DS can detect exactly the dyssynchrony of left ventricle.