Exploration of factors influencing shimming and water suppression on hepatic 1H-MR spectroscopy in vivo on 3.0 T
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.issn.1005-1201.2009.07.019
   		
        
        	
        		- VernacularTitle:在体肝脏3.0T1H-MR波谱匀场及抑水影响因素探讨
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Changhong LIANG
			        		
			        		;
		        		
		        		
		        		
			        		Li XU
			        		
			        		;
		        		
		        		
		        		
			        		Zaiyi LIU
			        		
			        		;
		        		
		        		
		        		
			        		Yanhai CUI
			        		
			        		;
		        		
		        		
		        		
			        		Chunling LIU
			        		
			        		;
		        		
		        		
		        		
			        		Junhui ZHENG
			        		
			        		;
		        		
		        		
		        		
			        		Qiongxin ZENG
			        		
			        		
		        		
		        		
		        		
		        		
		        		
			        		
			        		
		        		
	        		
        		 
        	
        	
        	
        		- Publication Type:Journal Article
 
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Liver;
			        		
			        		
			        		
				        		Fatty liver;
			        		
			        		
			        		
				        		Magnetic resonance spectroscopy
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Radiology
	            		
	            		 2009;43(7):739-742
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Objective To characterize the clinical factors which influence water suppression and auto-shimming line width for liver 3.0 T 1H-MRS.Methods Fifty-seven cases with liver 1H-MR spectroscopy(1H-MRS) were retrospectively studied, including chronic type B hepatitis (n=5), fatty liver (n=14), chronic type B hepatitis combining fatty liver (n=3) and normal situation (n=35).Independent t test was used to characterize the difference of general condition (height, weight, body mass index etc.) between different water suppression effect groups and between different shimming effect groups.Using Chi-square test to analyze whether water suppression rate and auto-shimming line width between fatty liver groups and non-fatty liver exist significance difference .Results By comparing WS ≥90% (n=47)group with WS < 90% (n=10) group, the former showed smaller average height[(164.7±8.0) and (170.5±3.7) cm respectively], weight[(61.8±10.4) and (73.4±5.4) kg respectively], BMI [(22.7±3.2) and (25.2±1.3)kg/m2 respectively]and LW[(17.7±3.7)and(24.6±6.3) Hz respectively]than the latter (t=-3.488,-3.415,-4.002 and-3.327, P < 0.05).By comparing LW 20 Hz (n=41) group with LW 20 Hz (n=16) group, the former showed better water suppression rate [(93.0±2.7)% and (86.1±8.5)% respectively]than the latter(t=3.213,P <0.05), whereas larger weight[(62.2±11.6) and (68.1±6.1)kg respectively]and BMI[(22.8±3.4) and (24.2±1.9)kg/m2 respectively](t=-2.516,-2.024,P <0.05).LW≤20 Hz in the fatty liver and non-fatty liver group was 7/17 and 34/40, respectively (X2=11.347, P < 0.05).WS < 90% in the fatty liver and non-fatty liver group was 10/17 and 0/44, respectively (X2=28.536, P < 0.05) .Conclusion Hepatic steatosis exerts an adverse effect in water suppression and shimming.