Knock-down of miR-221 and miR-222 in the radiosensitization of breast cancer cells
10.3760/cma.j.issn.1004-4221.2009.05.419
- VernacularTitle:敲低miR-221、miR-222表达对乳腺癌细胞放射敏感性影响的研究
- Author:
Chunzhi ZHANG
;
Chunsheng KANG
;
Yongzhen CAO
;
Peiyu PU
;
Zhonghong Lü
;
Yue DU
- Publication Type:Journal Article
- Keywords:
Cell lines;
breast neoplasms;
MicroRNA;
Radiosensitivity;
PTEN protein
- From:
Chinese Journal of Radiation Oncology
2009;18(5):419-422
- CountryChina
- Language:Chinese
-
Abstract:
cells, the expression of PTEN was up-regulated while pAkt down-regulated. Conclusions AS-miR-221 and AS-miR-222 may enhance the radiosensitivity of MCF-7 breast cancer cells by up-regulating the expression of PTEN.
