Lipoprotein-associated phospholipase A2 and carotid atherosclerosis
10.3760/cma.j.issn.1673-4165.2009.06.011
- VernacularTitle:脂蛋白相关磷脂酶A2与颈动脉粥样硬化
- Author:
Shujuan DAI
;
Qinglong AI
- Publication Type:Journal Article
- Keywords:
phospholipase A2;
carotid disease;
atherosclerosis
- From:
International Journal of Cerebrovascular Diseases
2009;17(6):459-462
- CountryChina
- Language:Chinese
-
Abstract:
Lipoprotein-associated phospholipase A2(Lp-PLA2) is a novel biomarker for cardiovascular disease. Its expression in symptomatic carotid plaques is higher than that in asymptomatic ones, and its product lysophosphatidylcholine is associated with tissue oxidative stress and inflammation. In addition, Lp-PLA2 plays a more unique role in the unstable difference of carotid atherosclerotic plaques.
